Dr. Patrick Mantyh received his Ph. D. in neuroscience from the University of California, San Francisco in 1981 and completed a postdoctoral fellowship in pharmacology at the University of Cambridge in 1983. Dr. Mantyh's lab first developed a model of bone cancer pain in 1999 and then a model of bone fracture pain in 2007. These models are now used by labs around the world. More recently, his focus has been to investigate the cellular and molecular mechanisms that regulate musculoskeletal pain and bone remodeling, and to use these findings in the development of novel therapies that reduce skeletal pain and promote skeletal health and successful aging.